Nearly 170 million people, including 95 million children, need humanitarian support in the region.
Eight countries are directly covered in this regional appeal due to climate-related shocks, health emergencies, including coronavirus disease 2019 (COVID-19), conflict, economic deterioration and displacement.
Countries are also struggling with poverty and food insecurity.
The United Republic of Tanzania and Zambia are hosting and responding to the needs of more than 360,000 refugees from Burundi and the Democratic Republic of the Congo, including 200,000 children on the move.
In collaboration with partners, UNICEF will deliver life-saving services for children, women and families affected by climatic shocks and disease outbreaks, including populations living in displacement and refugee camps.
Emphasis will be on mitigating disruptions resulting from the COVID-19 pandemic, while ensuring the continuity of essential services for health, nutrition, water, sanitation and hygiene (WASH), HIV, child protection, gender-based violence, education and social protection.